Appeal No. 2001-1925 Page 4 Application No. 08/677,838 The one relevant portion of the rejection discusses the examples in the specification, and the results as presented by the Figures of the application of the nuclease solution to the skin for the reduction of wrinkles. That portion of the rejection is reproduced below. Though the specification provides examples were [sic] the nuclease solution is applied to the skin, the results of these examples (i.e., the photographs) are equivocal. For instance, in Figures 1, 2, and 3, it is not possible to accurately assess the amount of wrinkling present due to the differences in lighting and facial expression. In this example, the specification states that Figure 1 is a photograph of a sixty-four year old female before treatment with the invention, and that Figure 2 is a photograph of the same woman after treatment. However, upon observation, the notable differences in the lighting preclude an accurate assessment of the amount of wrinkling and discoloration. Furthermore, while the photograph in Figure 3 is a clear, close-up profile shot of the same woman after treatment, her facial expression is different (i.e., not smiling which alone reduces folds around the eyes), and moreover, the disclosure fails to provide a corresponding before treatment photograph with which to accurately compare the results. Likewise, Figures 4, 5, and 6 are ambiguous as well. Figures 4 and 4 are the before treatment photographs of a forty-three year old female, yet once again, the lighting combined with the distance are such that no fine details of the skin can be ascertained in Figure 4. Accordingly, that leaves Figure 5 as the only before treatment close-up photograph with which to compare to the after treatment photographs of Figures 6 and 7. Yet, in this photograph (Figure 5) the woman appears to be squinting, something which she is not doing in the other photographs (Figures 6 & 7). Consequently, the absence of the folds present around the eye in Figures 6 and 7 could be the result of her facial expression or the absence thereof (i.e., no squinting). In addition, the pictures do not even address the ability of the claimed method to reduce skin discoloration. Accordingly, the pictures are equivocal and do not support the notion that the claimed method will in fact reduce wrinkles and discoloration in the skin. Answer, pages 3-4.Page: Previous 1 2 3 4 5 6 7 8 NextLast modified: November 3, 2007