Ex Parte TACKETT - Page 6


                 Appeal No. 2001-1925                                                           Page 6                    
                 Application No. 08/677,838                                                                               

                 the specification fails to provide an enabling disclosure.  The rejection does not                       
                 set forth other factors, such as the unpredictability of the art or the level of skill in                
                 the art that would support the analysis of the pictures in the rejection, and                            
                 buttress the conclusion that the specification fails to provide an enabling                              
                 disclosure.1  Thus, the examiner has failed to meet the burden of setting forth a                        
                 prima facie case of enablement, and the rejection is reversed.                                           
                                                  OTHER MATTERS                                                           
                         Upon return of the application, the examiner may wish to look at the                             
                 format of claim 1.  Claim 1 specifies that the nuclease solution is comprised of                         
                 components (a), (b) and (c).  There is also a limitation of the claim labeled with                       
                 (d), which would also make it a component of the nuclease, but the limitation is                         
                 actually drawn to the step of applying the solution to the skin.  Thus, it appears                       
                 as if the “(d)” should be deleted from the beginning of the application step in                          
                 order to avoid confusion.                                                                                











                                                                                                                          
                 1 The two references discussed in the rejection as evidence of the                                       
                 unpredictability of the art, i.e., Tackett and Pacifici, are again directed to the                       
                 putative theory of operation of the invention, and not the treatment of wrinkles                         
                 and age spots generally.                                                                                 





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