Ex Parte MONTAGNIER et al - Page 14



                 Appeal No. 2000-1929                                                                                 
                 Application No. 08/019,297                                                                           

                 carried out by an inventor, or exemplified in the specification, reasonable detail                   
                 must be provided in order to enable members of the public to understand and                          
                 carry out the invention.”).  “[T]he law requires that the disclosure in the                          
                 application shall inform them how to use, not how to find out how to use for                         
                 themselves.”  In re Gardner, 427 F.2d 786, 789, 166 USPQ 138, 141 (CCPA                              
                 1970).                                                                                               
                        Appellants argue that                                                                         
                        Following the teachings of the specification, the skilled artisan could                       
                        also use these antibodies to bind a labeled secondary antibody. . . .                         
                        Consequently, the skilled artisan needs no undue experimentation                              
                        to make and use the antibodies.                                                               
                 Appeal Brief, page 21.                                                                               
                        This argument is not persuasive.  The claimed antibodies are                                  
                 “directed against an antigen . . .selected from p25, p15, p36, p42, and                              
                 p80.”  See claim 45.  Thus, the claimed antibodies do not “bind a labeled                            
                 secondary antibody,” as Appellants assert; rather, they bind one of the                              
                 specified HIV proteins.3  The specification discloses no method for using                            
                 the instantly claimed antibodies, directed against p15, p36, p42, or p80,                            
                 and therefore fails to teach those skilled in the art how to use the claimed                         
                 invention.                                                                                           


                                                                                                                      
                 3 The claimed antibodies might be bound by a labeled secondary antibody, but at best that would      
                 be relevant to teaching how to use the labeled secondary antibody.  In any case, since the           
                 specification teaches that the HIV envelope proteins are not useful diagnostically (page 9, lines    
                 11-13), the specification provides no context in which a skilled artisan would use an                
                 immunoassay for detecting the instantly claimed antibodies.                                          

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