Ex Parte DARNELL et al - Page 6


                 Appeal No.  2001-0121                                                          Page 6                    
                 Application No.  08/212,185                                                                              
                                                                                                                         
                 of the invention, the state of the prior art, the relative skill of those in the art, the                
                 predictability or unpredictability of the art, and the breadth of the claims.                            
                         We find no analysis of the Wands factors by the examiner.  Instead, we                           
                 find only the examiner’s unsupported conclusions as to why the specification                             
                 does not enable the claimed invention.  We remind the examiner that nothing                              
                 more than objective enablement is required, and therefore it is irrelevant whether                       
                 this teaching is provided through broad terminology or illustrative examples. In re                      
                 Marzocchi, 439 F.2d at 223, 169 USPQ at 369.  In the absence of a fact-based                             
                 statement of a rejection based upon the relevant legal standards, the examiner                           
                 has not sustained her initial burden of establishing a prima facie case of non-                          
                 enablement.  The burden of proof does not shift to appellant until the examiner                          
                 first meets her burden.  Id., 439 F.2d at 223-224, 169 USPQ at 369-370.  We                              
                 recommend that the examiner review Enzo Biochem, Inc. v. Calgene, Inc., 188                              
                 F.3d 1362, 52 USPQ2d 1129 (Fed. Cir. 1999), wherein our appellate reviewing                              
                 court provided a model analysis of enablement issues and illustrated the type of                         
                 fact finding which is needed before one is in a proper position to determine                             
                 whether a given claim is enabled or non-enabled.                                                         
                         For the reasons set forth above, we are compelled to reverse the rejection                       
                 of claim 96-103 under 35 U.S.C. § 112, first paragraph.                                                  
                 THE REJECTION UNDER 35 U.S.C. § 102:                                                                     
                         According to the examiner (Answer, page 6), Decker “disclose assays in                           
                 which binding of activated RRFs to DNA added to cellular extracts was                                    








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