Appeal No. 2001-0163 Application No. 08/951,502 drawing out a solution rich in the other substances being non-adsorbable or poorly adsorbable on the particles of polysaccharide derivatives via the outlet port of another one of the columns; introducing an eluent into still another one of the columns via the inlet port thereof; drawing out a solution rich in the adsorbable or strongly adsorbable substances via the outlet port of further another one of the columns; and passing the remaining solution and the eluent through the circuit and recirculating them, wherein the position for introducing the eluent, the position for drawing out the solution containing the adsorbable or strongly adsorbable substances, the position for introducing the optical isomer mixture and the position for drawing out the solution containing the non-adsorbable or weakly adsorbable substances are arranged in the circulation in this order along the direction of the fluid flow, and the positions are successively moved in the direction of the fluid flow in the circuit intermittently. - 3 -Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007