Appeal No. 2001-0550 Application No. 09/030,792 is common knowledge in the art that trypsin functions most optimally at temperatures above room temperature, it is not clear to us that preheating the enzyme solution would be of any practical benefit in the practice of Spina’s method. As we see it, given the relatively long time period (12-96 hours) over which Spina’s enzyme works, and the elevated temperature that exists within the eye relative to room temperature, it may very well be that any initial preheating of the enzyme would have, at best, only a negligible effect on the overall efficiency of Spina’s method. The mere fact that the prior art could be so modified would not have made the modification obvious unless the prior art suggested the desirability of the modification (see In re Gordon, 733 F.2d 900, 902, 221 USPQ 1125, 1127 (Fed. Cir. 1984)). Spina contains no such suggestion. For these reasons, the rejection of claim 1, as well as claims 2, 9 and 11 that depend therefrom, as being anticipated by or, in the alternative, obvious in view of Spina will not be sustained. 13Page: Previous 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 NextLast modified: November 3, 2007