Ex Parte ANDREW et al - Page 8



          Appeal No. 2001-0550                                                        
          Application No. 09/030,792                                                  

          heating a thermally conductive fluid disposed within the organ”             
          (column 1, lines 8-14).  In Masterson, a thermally conductive               
          fluid and a heating apparatus are introduced into the hollow body           
          organ, and the heating apparatus is then activated to heat the              
          fluid within the hollow body organ.  A further explanation of the           
          heating apparatus and how it works is found at column 7, lines              
          31-52.  The fluid is heated to a temperature in the range from              
          about 60°C to 100°C (140°F to 212°F) to necrose or destroy the              
          lining of the organ (column 6, lines 3-6; column 6, line 66 to              
          column 7, line 1).  Masterson’s device includes an impeller 50              
          within the hollow body organ for circulating the fluid to provide           
          a more uniform temperature distribution.  The impeller                      
          additionally functions to cut up clots or tissue particles which            
          may be in the fluid and which can affect the temperature                    
          distribution (column 7, lines 62-67; column 10, lines 3-6).                 
               Method claim 1 includes the step of presenting heated fluid            
          to target tissue “so that said target tissue is liquefied,” and             
          the step of “aspirating said melted target tissue.”  Concerning             
          liquefying target tissue, the examiner contends that                        
               the provision that the target tissue be liquefied in                   
               the claim would seem to be carried out during the                      
               disclosed Masterson et al[.] process.  Since the                       
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