Ex parte VAZQUEZ et al. - Page 10


                      Appeal No.  2001-0598                                                                             Page 10                         
                      Application No.  08/451,090                                                                                                       
                      disclosure that the compounds set forth in ’795 would have any properties in                                                      
                      common with those of appellants’ compounds.                                                                                       
                               We remind the examiner that our appellate reviewing court has made it clear                                              
                      that there are no per se rules of obviousness or nonobviousness.  In re Ochiai, 71                                                
                      F.3d 1565, 1572, 37 USPQ2d 1127, 1133 (Fed. Cir. 1995)(“reliance on per se                                                        
                      rules of obviousness is legally incorrect.”)  Accord, In re Brouwer, 77 F.3d 422, 425,                                            
                      37 USPQ2d 1663, 1666 (Fed. Cir. 1996); In re Baird, 16 F.3d 380, 382, 29                                                          
                      USPQ2d 1550, 1552 (Fed. Cir. 1994).  Therefore, the fact that a claimed species                                                   
                      or subgenus is encompassed by a prior art genus is not sufficient by itself to                                                    
                      establish a prima facie case of obviousness.  See, Baird, 16 F.3d at 382, 29                                                      
                      USPQ2d at 1552 (“The fact that a claimed compound may be encompassed by a                                                         
                      disclosed generic formula does not by itself render that compound obvious.”); In re                                               
                      Jones, 958 F.2d 347, 350, 21 USPQ2d 1941, 1943 (Fed. Cir. 1992) (Federal                                                          
                      Circuit has “decline[d] to extract from Merck [ & Co. v. Biocraft Laboratories Inc.,                                              
                      874 F.2d 804, 10 USPQ2d 1843 (Fed. Cir. 1989)] the rule that ... regardless of how                                                
                      broad, a disclosure of a chemical genus renders obvious any species that happens                                                  
                      to fall within it.”).                                                                                                             




                               As the court recognized in Deuel, 51 F.3d at 1558, 34 USPQ2d at                                                          
                      1214-1215 in those cases where a prima facie case of obviousness is based upon                                                    
                      structural similarity “the prior art teaches a specific, structurally-definable compound                                          
                      and the question becomes whether the prior art would have suggested making the                                                    






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