Appeal No. 2001-0676 Application No. 08/941,132 page 5). Therefore, the skilled artisan would reasonably conclude that there would be little or no improvement in the efficiency of the graft-copolymerization and/or epoxidation reactions using the deproteinized rubbers, since the polypeptides from the naturally occurring proteins are still present and would impede the graft- copolymerization and/or epoxidation reactions in the same manner as would the naturally occurring proteins. According to the appellants and declarant (the Brief, pages 9-19 and the Miyamoto declaration, page 3), the improved efficiency in graft-copolymerization and epoxidation resulting from the deproteinization suggested by the applied prior art contrary to the skilled artisan’s expectation establishes that the claimed subject matter as a whole imparts unexpected results. It is not enough for the appellants to evince that the appellants’ invention produces an improvement. The improvement must be shown to be unexpected. In re Freeman, 474 F.2d 1318, 1324, 177 USPQ 139, 143 (CCPA 1973) In re Klosak, 455 F.2d 1077, 1080, 173 USPQ 14, 16 (CCPA 1972). Here, Yasuyuki teaches removing non-rubber components from natural rubber via a combination of known protein removing and reducing techniques. See page 2, lines 1-21. According to Yasuyuki (page 3, lines 46-48), proteins are eliminated from natural rubber to “such a level that it does not give an absorption at 3280 cm-1 in the infrared absorption spectrum, which is characteristic to polypeptides, when measured in 9Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 NextLast modified: November 3, 2007