The opinion in support of the decision being entered today was not written for publication and is not binding precedent of the Board. Paper No. 23 UNITED STATES PATENT AND TRADEMARK OFFICE __________ BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES __________ Ex parte MARK T. MARTIN __________ Appeal No. 2001-0940 Application No. 08/467,712 __________ ON BRIEF __________ Before WINTERS, WILLIAM F. SMITH, SCHEINER, Administrative Patent Judges. SCHEINER, Administrative Patent Judge. DECISION ON APPEAL This is an appeal under 35 U.S.C. § 134 from the final rejection of claims 12-17, all the claims remaining in the application. Claim 12 is representative of the subject matter on appeal and reads as follows: 12. A method for the determination of the concentration of an enzyme substrate present in a specimen, comprising the steps of: (a) contacting said specimen with an oxidoreductase conjugate under conditions which permit the oxidation of the enzyme substrate, said oxidoreductase conjugate comprising a co-factor and a species capable of generating an electrochemiluminescent signal separately linked in close proximity to an active site of said oxidoreductase in a manner which permits their electrochemical interaction with each other and a substrate also in close proximity to the active site; (b) measuring the change in electrochemiluminescence from a base reading; and (c) determining the concentration of enzymatic substrate based on the measured change in electrochemiluminescent signal. The references relied on by the examiner are: Nacamulli et al. (Nacamulli) 5,527,710 Jun. 18, 1996Page: 1 2 3 4 5 6 7 8 NextLast modified: November 3, 2007