Ex Parte ISHIGURO et al - Page 8


                 Appeal No. 2001-1045                                                         Page 8                    
                 Application No. 09/178,594                                                                             



                        Thus, the examiner has shown that Appellants are “claim[ing]                                    
                 embodiments of the invention that are completely outside the scope of the                              
                 specification.”  In re Alton, 76 F.3d at 1175, 37 USPQ2d at 1583.  He has                              
                 therefore carried his burden of showing a prima facie lack of adequate written                         
                 description.  Appellants have pointed to nothing in the specification literally                        
                 describing X and Y groups substituted with a thiocarbonyl substituent, nor have                        
                 they shown that those of skill in the art would have understood the specification                      
                 to show possession of such an embodiment.  We therefore we affirm the                                  
                 rejection of all the claims on this ground.                                                            
                 4.  Description and definiteness of R3                                                                 
                        Claim 15 defines the R3 group of the ester reactant as “a protective group                      
                 easily removed.”  The examiner rejected the claims on the basis that the                               
                 specification lacks an adequate description of R3 as defined in the claims.  He                        
                 noted that the specification defines R3 as follows:                                                    
                        The group represented by R3 is not particularly limited, only if it can                         
                        eliminate from the esterified carboxyl group represented by CO2R3                               
                        through hydrolysis or under conditions of the selective procedure                               
                        according to the type of esters, and its preferred examples include                             
                        those capable of forming the following esters:  [a long list of esters],                        
                        etc.                                                                                            
                 Specification, page 13, line 13, to page 14, line 34.                                                  
                        The examiner noted that, in contrast to the specification’s disclosure that                     
                 the protective group must be removable by hydrolysis or some kind of “selective                        
                 procedure,” the claim encompasses any protective group that is “easily                                 






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