Ex Parte VAN DYKE - Page 2



              Appeal No.  2001-1164                                                                 Page 2                 
              Application No. 08/293,745                                                                                   
























              Th                                                                                                           
              e Prior Art References                                                                                       
                     In rejecting the appealed claims under 35 U.S.C. § 103, the examiner relies on                        
              the following prior art references:                                                                          
              Kuroda et al. (Kuroda), "Antitumor Effect of Bisbenzylisoquinoline Alkaloids," Chem.                         
              Pharm. Bull., Vol. 24, No. 10, pp. 2413-2420 (1976)                                                          
              Kato et al. (Kato), Potentiation of Antitumor Activity of Vincristine by the Biscolaurine                    
              Alkaloid Chepharanthine," JNCI, Vol. 79, No. 3, pp. 527-532 (1987)                                           


              Liao, Chemical Abstract No. 93CA"197657u, "Effect of D-Tetrandrine and Thalicarpine,                         






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