Ex Parte HERSH - Page 11


                  Appeal No. 2001-1177                                                         Page 11                     
                  Application No. 08/781,868                                                                               

                  different use, and therefore claim 35 is unpatentable under 35 U.S.C. § 103.                             
                  Claims 37, 38, and 44 fall with claim 35.                                                                
                  B.  N’Guyen, Burke, and Levin                                                                            
                         The examiner rejected claim 43 as obvious over N’Guyen, Burke, and                                
                  Levin.  Claim 43 is directed to the composition of claim 35, with the additional                         
                  component tissue respiratory factor.  As the examiner noted, Levin teaches                               
                  topical compositions comprising tissue respiratory factor for treating skin                              
                  wrinkles, among other things.  See Levin, column 1, lines 34-35 and 65-68.  The                          
                  examiner concluded that it would have been obvious to combine the tissue                                 
                  respiratory factor disclosed by Levin with the composition comprising glutathione                        
                  and selenoamino acids taught by the combination of N’Guyen and Burke.                                    
                         We agree.  Levin teaches that tissue respiratory factor is useful in treating                     
                  skin wrinkles, and Burke teaches that wrinkles are one of the symptoms of                                
                  photoaging.  Thus, it would have been obvious to combine Levin’s tissue                                  
                  respiratory factor with the composition suggested by N’Guyen and Burke.  See                             
                  Kerkhoven, 626 F.2d at 850, 205 USPQ at 1072 (“It is prima facie obvious to                              
                  combine two compositions each of which is taught by the prior art to be useful for                       
                  the same purpose, in order to form a third composition which is to be used for the                       
                  very same purpose.”).                                                                                    
                         Appellant argues that “Levin teaches a topical composition including an                           
                  anti-inflammatory agent and live yeast cell derivative to ameliorate the neuralgic                       
                  pain associated with herpes infection when applied to an area of the skin                                
                  proximate the pain.  Once again, the combination of Levin with the principal                             





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