Ex Parte HERSH - Page 14


                  Appeal No. 2001-1177                                                         Page 14                     
                  Application No. 08/781,868                                                                               

                         The examiner argues that all of the references teach that the various                             
                  agents are useful in treating damaged skin, and therefore it would have been                             
                  obvious to combine them.  In our view, this characterization overstates the                              
                  breadth of the disclosures of Cavazza, Piazza, Finkenauer, Spector, and Otsu.                            
                  These references disclose certain agents to be useful in treating skin that is                           
                  suffering from a specific condition, not as useful in treating “damaged” skin                            
                  generally, regardless of the source of the damage.  Importantly, none of these                           
                  references discloses the various agents to be useful in treating age-damaged                             
                  skin, and therefore they would not have provided the requisite motivation to                             
                  combine their respective agents with the glutathione and selenoamino acids                               
                  taught by N’Guyen and Burke.                                                                             
                         The rejection of claims 36 and 39-42 under 35 U.S.C. § 103 is reversed.                           
                  D.  The method claims                                                                                    
                         The examiner rejected all of the method claims (claims 45-54) as obvious                          
                  over the combined disclosures of N’Guyen, Burke, Levin, Cavazza, Piazza,                                 
                  Finkenauer, Spector, and Otsu.  The examiner reviewed the disclosures of each                            
                  of the cited references and concluded that                                                               
                         [e]ach of these references discloses methods of treating free                                     
                         radical damaged skin by applying compositions comprising one or                                   
                         more of the recited ingredients.  These methods provide for the                                   
                         treatment of damaged skin, and/or the prevention of further                                       
                         damage to the skin.  It would have been obvious to one of ordinary                                
                         skill in the art to have used compositions comprising glutathione                                 
                         and selenoamino acids, as well as [the other recited agents] for the                              
                         repair of free radical damaged skin, as these ingredients have been                               
                         shown to be important and/or effective for the healing of free radical                            
                         damaged skin, and other types of injuries or damage.  Combination                                 
                         of these ingredients for use in the method of treatment would be                                  





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