Ex Parte NAKATANI et al - Page 5



             Appeal No. 2001-1264                                                              Page 5                
             Application No. 08/819,630                                                                              
             forth that the subset of cytokines which possess chemotaxis are generically named                       
             chemokines.                                                                                             
                    Where as here the metes and bounds of the claims cannot be readily                               
             determined, significant misstatements of fact are made and the rejections are based                     
             upon incorrect legal standards it is appropriate to vacate the rejections.                              
                                New Ground of Rejection Under 37 CFR § 1.196(b)                                      
                    Claims 7 through 10 and 13 are rejected under 35 U.S.C. § 112, second                            
             paragraph, as being indefinite.                                                                         
                    Each of the claims is directed to a method for removing a chemokine except                       
             interleukin-8.  In reviewing this claim language in light of the supporting specification,              
             we find the claims to be ambiguous as to their scope and meaning.                                       
                    We believe the reason the exception for interleukin-8 appears in the claims on                   
             appeal is the patent activity described by applicants at page 6 of the specification.  In               
             an exchange held at oral argument, counsel stated his understanding that the language                   
             of the claim excepting interleukin-8 from the claimed method is intended to serve as a                  
             disclaimer of the subject matter in a patent rights enforcement sense.  However,                        
             counsel’s argument only adds to the confusion as to the scope and meaning of the                        
             claims on appeal.                                                                                       
                    The claim language excepting interleukin-8 from the claimed method renders the                   
             claims ambiguous and unclear.  It is unclear from reading the claims in light of the                    
             specification whether interleukin-8 is not removed by the claimed adsorbent because                     
             the adsorbent is selected so that it adsorbs all chemokines except interleukin-8 or                     
             whether the process is to be operated with an adsorbent which is capable of adsorbing                   





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