Ex Parte NAKATANI et al - Page 6



             Appeal No. 2001-1264                                                              Page 6                
             Application No. 08/819,630                                                                              
             interleukin-8 under certain conditions but the method is operated in such a manner that                 
             the required selective adsorption of chemokines but for interleukin-8 occurs.                           
             Alternatively, it may be that the process must be operated such that the body fluid is                  
             pretreated to remove interleukin-8 prior to contact with the adsorbent.  Another                        
             possibility is that the patient is selected such that the condition they are suffering from             
             results in the presence of chemokines but for interleukin-8 so that treatment of body                   
             fluids from that patient would meet the stated exception.  Another way in which the                     
             claims may be interpreted is that the claims are intended to encompass removal of                       
             chemokines from a body fluid of a patient using an adsorbent so long as the adsorbent                   
             does not remove interleukin-8 exclusively.  In other words, the claimed method may                      
             encompass treatment of patients whose body fluids contain a number of chemokines                        
             including interleukin-8 so long as the adsorbent removes all chemokines including                       
             interleukin-8 while the claim would not include the treatment of such a patient if the                  
             adsorbent selectively removes interleukin-8 while not adsorbing any other chemokine.                    
                    When a claim is subject to so many alternative interpretations as to its metes                   
             and bounds and where the specification provides no guidance as to how the claims                        
             should be interpreted, the claims are fraught with ambiguity.  As set forth in  In re Zletz,            
             893 F.2d 319, 321-22, 13 USPQ2d 1320, 1322 (Fed. Cir. 1989):                                            
                           [D]uring patent prosecution when claims can be amended, ambiguities                       
                           should be recognized, scope and breadth of claim language explored, and                   
                           clarification imposed....An essential purpose of patent examination is to                 
                           fashion claims that are precise, clear, correct, and unambiguous.  Only in                
                           this way can uncertainties of claim scope be removed, as much as                          
                           possible, during the administrative process.                                              








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