Appeal No. 2001-2093 Application No. 09/054,134 278, 280 (CCPA 1976); In re Boe, 355 F.2d 961, 965, 148 USPQ 507, 510 (CCPA 1966). Regarding the use of concentrated sulfuric acid in DE ’715 (appeal brief, page 4), the appellants’ specification states that strong sulfuric acid may be used to control the pH to the recited range, as we pointed out above. Accordingly, we see no basis for concluding that the use of concentrated sulfuric acid favors a determination of nonobviousness. The appellants rely on the teachings of Seymour, Cram, Morrison, and The Encyclopedia of Polymer Science and Technology for the proposition that the “reactions of small molecules are not necessarily predictive of reactions of polymers.” (Appeal brief, page 6.) We agree with the appellants that the specific reaction conditions suitable for polymers may not necessarily be the same as the conditions for compounds. Nevertheless, the prior art suggests that the same variables would affect the results for alkylation reactions of tertiary amines, regardless of whether polymers or compounds are used as the starting materials. Thus, the prior art as a whole would have fairly suggested to one of ordinary skill in the art that temperature and pH are result-effective variables in the alkylation of polymers containing tertiary amines. Accordingly, it is our judgment that the discovery of workable or even optimum 7Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007