Ex Parte LUTJENS et al - Page 9


          Appeal No. 2001-2093                                                        
          Application No. 09/054,134                                                  

          CFR § 1.132 (1996) of Holger Lütjens,4 filed Feb. 23, 2000 (paper           
          18) as well as Example 1 and comparison Example 2 of the present            
          specification5 as objective evidence of nonobviousness (appeal              
          brief, pages 7-8), we concur with the examiner (final Office                
          action, page 4) that the proffered evidence is insufficient to              
          rebut the prima facie case of obviousness.                                  
               Specifically, we note that Example 1 and comparison Example            
          2 are not effective to demonstrate criticality for the claimed              
          pH and temperature ranges because these experiments differ by               
          more than solely the pH values and temperatures.  In particular,            
          477 kg of ethylene oxide are added over 2 hours and then the                
          mixture is stirred for 2 hours in Example 1.  By contrast, 550              
          kg of ethylene oxide are added over 4 hours in comparison                   
          Example 2.  In re Dunn, 349 F.2d 433, 439, 146 USPQ 479, 483                
          (CCPA 1965)(“While we do not intend to slight the alleged                   
          improvements, we do not feel it an unreasonable burden on                   
          appellants to require comparative examples relied on for non-               
          obviousness to be truly comparative.  The cause and effect                  


                                                                                     
               4  This declaration reports the “swelling stabilities of the           
          anion exchange polymers prepared according to Example 1 and                 
          comparison Example 2” of the present application.                           
               5  Example 1 and comparison Example 2 of the present                   
          specification report yield, total capacity, degree of                       
          quaternization, and content of low molecular weight polymers.               

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