Ex parte BONFILS et al. - Page 7




                   Appeal No. 2001-2138                                                                                                                             
                   Application No. 08/403,276                                                                                                                       
















                   where R represents                                                             hydrogen, a lower alkyl radical,                                  
                   or an acyl radical of a lower organic acid.  (RousselSUclaf I at 1, left column; Bertin at col.                                                  
                   1, ll.15–30.)                                                                                                                                    
                                      13.       These compounds may be named 3-OR-20-(N,N-                                                                          
                                                                      1,2,5(10)                                                                                     
                   dimethylaminoethylamino)-19-nor-)                         -pregnatrienes.  (RUSI at 1, right column, ll.5–6;                                     
                   Bertin at col. 2, ll.69–70, and Table I at col. 3 (chemical reaction scheme).)                                                                   
                                      14.       The compounds are disclosed to have antilipemic and                                                                 
                   hypocholesterolemiantic activities, and to lack any estrogenic activity.  (RUSI at 1, left                                                       
                   column, second paragraph;  Bertin at col. 2, ll.40–43.)                                                                                          
                                      15.       The disclosed synthesis of the inventive compounds begins with                                                      
                                                                                                   1,3,5(10)                                                        
                   compounds of formula II, such as 3-OR 20-oxo 19-nor )                                  -pregnatriene.  (RUS1 at 1,                               




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