Appeal No.2001-2506 Page 2
Application No. 08/415,658
13. Plasmid pSM651 deposited at the Bureau Voor
Schimmelcultures, SK Baarn (Holland) where it has received
the deposit number CBS 203.94.
14. A microorganism selected from Bacillus subtilis and
Escherichia coli transformed with the plasmid pSM651.
The examiner relies upon the following references:
Olivieri et al. (Olivieri) 4,312,948 Jan. 26, 1982
Neal et al. (Neal) WO 94/00577 Jan. 6, 1994
European Patent Application
Nanba et al. (Nanba) 0 515 698 Dec. 12, 1992
The claims stand rejected under 35 U.S.C. § 103(a). After careful review
of the record and consideration of the issues before us, we reverse.
BACKGROUND
The clams are drawn to a method of producing D-I-amino acids through
the stereospecific conversion of 5-substituted hydantoins. The conversion is
achieved through the use of a microorganism that has been transformed with a
plasmid capable of expressing D-hydantoinase and D-N-carbamoylase enzymes
without the introduction of an inducer. See Specification, page 1. The plasmid
required by the claims is the pSM651 plasmid, which has been deposited at the
Bureau Voor Schimmelcultures, SK Baarn (Holland), and has a deposit number
of CBS 203.94. See id. page 16.
DISCUSSION
Claims 1 and 4-15 stand rejected as obvious over the combination of Neal
and Nanda. Claims 2 and 3 stand rejected over the combination of Neal and
Nanda, further in view of Olivieri.
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