Ex Parte DURAN et al - Page 7




          Appeal No. 2003-0233                                                        
          Application 09/103,874                                                      


          col. 3, lines 35-36).                                                       
               The examiner argues that Baumgartner’s collagenous material            
          differs from that of the appellants only in that Baumgartner’s              
          collagenous material has not been heparinized (answer, page 6).             
          Even if, because Baumgartner’s treated collagenous material, like           
          that of the appellants (specification, page 4, lines 19-22), has            
          properties corresponding very well to the native tissue, it could           
          reasonably be considered to appear to be the same or                        
          substantially the same as the appellants’ collagenous material              
          before being heparinized, the examiner has not established a                
          prima facie case of obviousness.  The reason is that, as                    
          discussed above, the examiner has not established that the                  
          applied references themselves would have led one of ordinary                
          skill in the art to heparinize Baumgartner’s collagenous                    
          material.                                                                   



















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