Ex Parte BOCHES et al - Page 3



             Appeal No.  1999-0334                                                             Page 3                
             Application No. 08/150,747                                                                              
             over the same references in combination with Pourfarzaneh.1                                             
                    We reverse both of these rejections.                                                             
                                                   DISCUSSION                                                        
             The rejection of claims 34 and 35                                                                       
                    According to the examiner, Gutcho describes Aa competitive specific binding                      
             assay for folate and vitamin B12 in which the sample is first treated to release folate and             
             vitamin B12 from endogenous binders . . . then combined with labeled folate and vitamin                 
             B12 and immobilized binders for the folate and vitamin B12 . . . folate binder and intrinsic            
             factor [are mentioned] as suitable binders.@  Examiner=s Answer, page 3.  Høier-                        
             Madsen describes an immunoassay for detecting folate binding protein wherein folate                     
             binding protein is sandwiched between immobilized and labeled antibodies specific for                   
                                                                                                                    
                    1 According to appellants, A[t]he claims now on appeal were last amended in [the]                
             Response After Final Rejection dated October 20, 1997@ and A[t]hat amendment was                        
             entered by the Examiner in the examiner=s Advisory Action dated November 10, 1997.@                     
             Brief, page 2.  We note that claim 35, as amended, was rejected under 35 U.S.C. '                       
             112, second paragraph in that advisory action.  That rejection was never expressly                      
             withdrawn but was not repeated in the Examiner=s Answer.  We have therefore treated                     
             the rejection as having been withdrawn.                                                                 


















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