Ex Parte BOCHES et al - Page 6



             Appeal No.  1999-0334                                                             Page 6                
             Application No. 08/150,747                                                                              
             analyte,@ (Id., page 7), thus, A[t]he binding protein . . . must retain the ability to bind with        
             its analyte and/or labeled analyte while . . . [bound] to the primary antibody@  (Id., page             
             8).                                                                                                     
                    More importantly, A[i]n the suggested combination, an anti-antibody is on the                    
             solid phase (Litt), then an antibody which binds folate binding protein (Høier-Madsen) is               
             bound to that anti-antibody.@  Brief, page 6.  Again, as pointed out by appellants, A[t]his             
             is not the present invention.@  Id.  Appellants argue essentially that the examiner=s                   
             rationale for combining the references would tend to show that appellants Ahave                         
             proceeded contrary to the accepted wisdom of the prior art.@  Brief, page 7.  Appellants=               
             point is well taken, inasmuch as the examiner=s rationale is entirely concerned with                    
             using a double antibody solid support or an intermediate binding structure to improve                   
             antibody binding and stability, yet the claimed invention requires no such arrangements.                
                    AThe name of the game is the claim,@ In re Hiniker Co., 150 F.3d 1362, 1369, 47                  
             USPQ2d 1523, 1529 (CAFC 1998).  Here, we have no reasoned statement from the                            
             examiner as to why the claimed invention would have been unpatentable under 35                          
             U.S.C. ' 103.  The fact that the prior art could have been modified in a manner                         
             consistent with appellants= claims would not have made the modification obvious unless                  
             the prior art suggested the desirability of the modification.  In re Gordon, 733 F.2d 900,              
             902, 221 USPQ 1125, 1127 (Fed. Cir. 1984).  Here, we find no reason stemming from                       
             the prior art relied on by the examiner which would have led a person having ordinary                   
             skill in the art to the claimed invention.  On this record, the only reason or suggestion to            
             combine the references in the manner claimed comes from appellants= specification.                      
             Accordingly, we reverse the rejection of claims 34 and 35 under 35 U.S.C. ' 103.                        
             The rejection of claim 33                                                                               



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