Ex Parte BOCHES et al - Page 7



             Appeal No.  1999-0334                                                             Page 7                
             Application No. 08/150,747                                                                              
                    Claim 33 is directed to a method of determining the amount of vitamin B12 in a                   
             sample; the format is the same as that of claim 34, but the analyte is vitamin B12, the                 
             binding protein is intrinsic factor, and the primary antibodies are specific for intrinsic              
             factor.  The examiner=s proposed combination of Gutcho, Litt, Suter and Høier-Madsen                    
             forms the basis of this rejection as well, with the addition of Pourfarzaneh as evidence                
             that Aantibodies to intrinsic factor:vitamin B12 complex and immunoassays for vitamin                   
             B12 using the antibodies@ were known in the art.  The addition of Pourfarzaneh does                     
             nothing to cure the underlying deficiency in the proposed combination of Gutcho, Litt,                  
             Suter and Høier-Madsen, thus, the rejection of claim 33 under 35 U.S.C. ' 103 is                        
             reversed as well.                                                                                       
                                                    REVERSED                                                         





                                                                    )                                                
                                  William F. Smith                 )                                                
                                  Administrative Patent Judge       )                                                
                                                                    )                                                
                                                                    )                                                
                                                                    ) BOARD OF PATENT                                
                                                                    )                                                
                                  Toni R. Scheiner                  ) APPEALS AND                                    
                                  Administrative Patent Judge       )                                                
                                                                    ) )INTERFERENCES                                 
                                                                    )                                                
                                                                    )                                                
                                                                    )                                                
                                  Demetra J. Mills                 )                                                
                                  Administrative Patent Judge       )                                                








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