Appeal No. 1999-0334 Page 7 Application No. 08/150,747 Claim 33 is directed to a method of determining the amount of vitamin B12 in a sample; the format is the same as that of claim 34, but the analyte is vitamin B12, the binding protein is intrinsic factor, and the primary antibodies are specific for intrinsic factor. The examiner=s proposed combination of Gutcho, Litt, Suter and Høier-Madsen forms the basis of this rejection as well, with the addition of Pourfarzaneh as evidence that Aantibodies to intrinsic factor:vitamin B12 complex and immunoassays for vitamin B12 using the antibodies@ were known in the art. The addition of Pourfarzaneh does nothing to cure the underlying deficiency in the proposed combination of Gutcho, Litt, Suter and Høier-Madsen, thus, the rejection of claim 33 under 35 U.S.C. ' 103 is reversed as well. REVERSED ) William F. Smith ) Administrative Patent Judge ) ) ) ) BOARD OF PATENT ) Toni R. Scheiner ) APPEALS AND Administrative Patent Judge ) ) )INTERFERENCES ) ) ) Demetra J. Mills ) Administrative Patent Judge )Page: Previous 1 2 3 4 5 6 7 8 NextLast modified: November 3, 2007