Ex Parte RUSSELL et al - Page 4



            Appeal No. 1999-1397                                                          Page 4              
            Application No. 08/303,924                                                                        
            and electronic detection means provides for a more complete analysis of the cells                 
            because together, these measurements provide the ability to differentiate at least five           
            types of leukocytes,@ and A[t]he three sensing parameters are conventional in the art . . .       
            and thus a skilled artisan would have had a reasonable expectation of success in                  
            combining all three for a complete analysis of the WBC subsets.@  Examiner=s Answer,              
            page 4.                                                                                           
                   Appellants argue that all of the claims on appeal require microspheres between             
            about 0.65 and 3.0 microns in diameter, but Athis size range is nowhere to be found in            
            the cited references.@  Brief, page 7.  We note that this size range is not mentioned in          
            the statement of the rejection either.  Nevertheless, in responding to appellants=                
            argument, the examiner concludes that even though Kortright Adoes not specifically                
            teach the size of the microspheres, it is obvious from [Kortright=s] description that the         
            microspheres should be smaller than the cells so that a plurality of microspheres is              
            attached to the cells.@  Examiner=s Answer, page 6.                                               
                   On first impression, the examiner=s conclusion does not appear to be                       
            unreasonable, but there is no objective evidence of record to support it.  It is improper         
            for this board, and for that matter the examiner, to hold claims unpatentable for                 
            obviousness based on conclusory statements about what can be characterized as                     
            Acommon knowledge@ or Acommon sense,@ without objective evidence in support of that               
            knowledge.  See In re Lee, 277 F.3d 1338, 1344, 61 USPQ2d 1430, 1434-1435 (Fed.                   
            Cir. 1992).  In any case, there is evidence of record, which the examiner has not                 
            addressed, that would seem to undermine the examiner=s position.  According to                    
            appellants (Reply Brief, page 1), Suzuki Aexpressly discloses attaching microspheres to           





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