Ex Parte YIANNI - Page 3


                 Appeal No.  1999-2816                                                     Page 3                   
                 Application No.  08/064,052                                                                        

                 (id.) that “[t]he materials come in contact with blood during testing [and that] ‘a                
                 remarkable reduction in thrombogenicity’ is demonstrated by compounds                              
                 containing a phosphatidylcholine group.”  The examiner finds (Answer, page 5)                      
                 that Bird “suggests the use of the phosphatidyl choline [sic] material as a                        
                 biomaterial to be used in a device which would be implanted in the body (note,                     
                 e.g. the suggestion of benefits for grafts in an arterial tree, p. 481, second full                
                 paragraph).”  From this the examiner concludes (Answer, page 4) “[b]ecause the                     
                 prior art uses one of the materials specifically named in the present claims to                    
                 coat a surface, it is the examiner’s position that the lubricity of the surface which              
                 is coated is increased and the thrombogenicity of the surface which is coated is                   
                 decreased.”                                                                                        
                       In response, appellant argues inter alia (Brief3, page 6) “the lubricity of the               
                 coated components in Bird is not disclosed … [therefore,] a skilled person,                        
                 seeking a way of improving the lubricity of single-use disposable items which are                  
                 to be inserted into the body … would not be led to consider the teachings of Bird                  
                 as relevant.”                                                                                      
                       In response, the examiner argues (Answer, page 6) “that the benefits of                      
                 reduced thrombogenicity, alone, would have motivated one of ordinary skill in the                  
                 art at the time of the invention to apply a coating of the phosphatidylcholine                     
                 material to a surface of a device where reduced thrombogenicity was desired.”                      



                                                                                                                    
                 3 Paper No. 28, received July 21, 1997.                                                            





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