Ex Parte GRADY et al - Page 6


                 Appeal No.  2001-1499                                                          Page 6                  
                 Application No. 08/957,654                                                                             
                 (Brief, page 13) Clark adds nothing to the shortcomings of the examiner’s                              
                 position concerning the broad and unfocused disclosure of Schwarz.                                     
                        In response, the examiner explains (Answer, page 9), that claim 9, as it                        
                 depends from claim 7, “is a composition claim, and an intended use limitation                          
                 does not impart patentability to a composition claim in which the composition is                       
                 otherwise … obvious over the prior art.”  We agree.                                                    
                        As explained by the examiner (Answer, page 3), Schwarz “teach a                                 
                 composition for use in healing wounds in which the composition can comprise                            
                 0.5-90 mg/ml alpha-1-antitrypsin.”  Furthermore, example 5 of Schwarz details                          
                 such a composition comprising 10mg/ml of AAT.  Clark discusses a transgenic                            
                 method to provide a convenient source of large amounts of medically important                          
                 human proteins, including AAT.  Clark, pages 1-3.  In our opinion, the evidence                        
                 of record weighs in favor of the examiner.  Accordingly, we affirm the rejection of                    
                 claim 9 under 35 U.S.C. § 103 as being unpatentable over Schwarz in view of                            
                 Clark.                                                                                                 
                 Gillis:                                                                                                
                        According to the examiner (Answer, page 4), Gillis “teaches treating                            
                 wounds including chronic wounds such as chronic bedsores and ulcerative skin                           
                 conditions by administering a composition comprising IL-1 and optionally alpha-                        
                 antitrypsin.”  The examiner, however, recognizes (Answer, page 5), Gillis “do not                      
                 teach that alpha-antitrypsin in and of itself has any intrinsic chronic wound-                         
                 treating properties.”  Nevertheless, the examiner maintains (Answer, page 4) that                      








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