Appeal No. 2001-2643 Page 2
Application No. 08/117,363
where:
RA is alkyl having from 1 to about 10 carbon atoms or (CH2-CH2-Q)x;
R1a and R1b, independently, are H, R2, or an amine protecting group
or have formula C(X)-R2, C(X)-RA-R2, C(X)-Q-RA-R2, C(X)-Q-R2; and
R2 is a folate, a steroid molecule, a reporter molecule, a lipophilic
molecule, a reporter enzyme, a peptide, a protein, or has formula
-Q-(CH2CH2-Q-)X-R3;
X is O or S;
each Q is independently, is NH, O, or S;
x is about 1 to about 50;
R3 is H, RA, C(O)OH, C(O)ORA, C(O)R4, RA-N3, or RA- NH2;
R4 is Cl, Br, I, SO2 R5 or has structure:
m is 2 to 7; and
R5 alkyl having 1 to about 10 carbon atoms.
The examiner relies on the following references:
Urdea et al. (Urdea) 4,910,300 Mar. 20, 1990
Carrico 4,743,535 May. 10, 1988
Matteucci WO 92/05186 Apr. 02, 1992
Latham WO 91/14696 Oct. 03, 1991
Claims 1-4, 6-18, and 20-29 stand rejected under 35 U.S.C. § 103 as
obvious in view of Urdea, Carrico, Matteucci, and Latham.
Claims 5 and 19 stand rejected under 35 U.S.C. § 103 as obvious in view
of Urdea, Carrico, Matteucci, Latham, and “applicant[’]s admissions.”
We reverse.
Page: Previous 1 2 3 4 5 6 7 8 9 Next
Last modified: November 3, 2007