Appeal No. 2002-0230 Application No. 09/136,070 identified above. The mere fact that the prior art could be modified as proposed by the Examiner is not sufficient to establish a prima facie case of obviousness. See In re Fritch, 972 F.2d 1260, 1266, 23 USPQ2d 1780, 1783 (Fed. Cir. 1992). We agree with Appellants that the Examiner’s conclusion that it would have been obvious to move the location of the connection hole to the bottom of the reagent container of Rokugawa is unsupported by any teaching in the prior art. (Brief, p. 5). The Examiner asserts “[i]t would have been obvious to one having ordinary skill in the art at the time the invention was made to have locate the connection hole at the bottom of the reagent container in order to allow the reagent to be dispensed under the force of gravity, thereby eliminating the need for extra pressure head.” (Answer, paragraph bridging pages 4 -5). Additionally, the Examiner asserts “the location at the bottom-most surface of the reagent container ensures that the entire reagent is removed.” (Answer, p. 6). The record indicates that the motivation relied upon by the Examiner for moving the location of the connection hole comes from the Appellants’ description of their invention in the specification, pages 16-18, rather than coming from the applied prior art and that, therefore, the Examiner used impermissible hindsight in rejecting the claims. See W.L. Gore & Associates v. Garlock, Inc., 721 F.2d 1540, 1553, 220 USPQ 303, 312-13 (Fed. Cir. 1983); In re -6-Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 NextLast modified: November 3, 2007