Ex Parte COOK et al - Page 7




          Appeal No. 2002-0795                                                        
          Application No. 09/128,036                                                  

          explain why the structural similarity of the compounds produced             
          by Cody and Smith would have motivated one of ordinary skill in             
          this art to modify the reactants and method used in obtaining the           
          products, especially in view of the teaching away from mixtures             
          found in Cody.                                                              
               Finally, the examiner states another alternate motivation to           
          combine the references, i.e., Smith teaches use of mixtures of              
          reactants “to be able to screen a large number of diverse                   
          compounds in a short timespan” (Answer, page 8).  However, the              
          examiner has not explained or presented evidence why one of                 
          ordinary skill in this art would have modified the method of Cody           
          in view of this teaching of Smith since Cody also teaches                   
          screening a large number of compounds in a short timespan (the              
          time of the simultaneous reactions).                                        
               For the foregoing reasons and those stated in the Brief and            
          Reply Brief, we determine that the examiner has not established             
          any motivation to combine the references as proposed and                    
          therefore we determine that no prima facie case of obviousness              
          has been presented.  Accordingly, the rejection of the claims on            
          appeal under 35 U.S.C. § 103(a) over Cody in view of Smith is               
          reversed.                                                                   



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