Ex Parte MAYR - Page 6


                    Appeal No.  2002-1291                                                                  Page 6                       
                    Application No.  08/693,052                                                                                         

                    undue amount of experimentation to practice the full scope of the claimed                                           
                    subject matter.  Moreover, the fact that the claims may encompass inoperative                                       
                    embodiments does not render them non-enabled.  See Atlas Powder Co. v. E.I.                                         
                    Du Pont De Nemours & Co., 750 F.2d 1569, 1576, 224 USPQ 409, 413 (Fed.                                              
                    Cir. 1984), In re Angstadt, 537 F.2d 498, 504, 190 USPQ 214, 218 (CCPA                                              
                    1976).                                                                                                              
                    2.     35 U.S.C. § 102(b)                                                                                           
                           Claims 19, 20, 21, 27 and 28 stand rejected under 35 U.S.C. § 102(b) as                                      
                    being anticipated by Mayr II.  Claim 19 is treated as the representative claim, as                                  
                    the claims stand or fall together.  See Appeal Brief, page 7.                                                       
                           According to the rejection:                                                                                  
                           Mayr [II] disclose[s] administering the combination of ORF virus                                             
                           strain D1701, attenuated by 135 passages in secondary cell                                                   
                           cultures of embryonic sheep kidneys and subsequently grown in                                                
                           bovine embryo lung cells (see the Summary, page 550), and the                                                
                           paramunity inducer DUPHAMEN®, which is disclosed in the instant                                              
                           specification as being attenuated avipox virus strain HP-1, as a                                             
                           sheep vaccine (see the Summary, page 550, pages 545-546 and                                                  
                           the Abstract, for example.)  Although it is recognized that Mayr [II]                                        
                           administered the ORF virus D1701 for the purpose of inducing                                                 
                           specific immunity in sheep, and administered it in combination with                                          
                           a paramunity inducer, the composition of Mayr [II] is deemed to                                              
                           anticipate the claimed composition since it combines two of the                                              
                           same poxvirus strains that are encompassed by the instant claims                                             
                           and that are specifically recited in claim 21, regardless of the                                             
                           purpose for which Mayr [II] intended it or the reason Mayr [II]                                              
                           combined the two strains.  The specification at page 9 describes                                             
                           procedures for attenuation of ORF virus D1701 for use as a                                                   
                           paramunity inducer that reasonably appear to be equivalent to the                                            
                           attenuation procedures described by Mayr [II]; further, the                                                  
                           specification at page 4, lines 24-28, points out that attenuation by                                         
                           multiple passages in cell cultures causes immunizing properties to                                           
                           decrease and paramunizing properties to increase.  Consequently,                                             
                           the claim limitations are met by the combination of attenuated ORF                                           





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