Ex Parte NAGGI et al - Page 5




                 Appeal No. 2002-1356                                                                                                             
                 Application No. 09/206,063                                                                                                       
                 of presenting a prima facie case of obviousness.  See In re Rijckaert, 9 F.3d 1531,                                              
                 1532, 28 USPQ2d 1955, 1956 (Fed. Cir. 1993).   It is well-established that the                                                   
                 conclusion that the claimed subject matter is prima facie obvious must be supported by                                           
                 evidence, as shown by some objective teaching in the prior art or by knowledge                                                   
                 generally available to one of ordinary skill in the art that would have led that individual to                                   
                 combine the relevant teachings of the references to arrive at the claimed invention.                                             
                 See In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598 (Fed. Cir. 1988).                                                       


                 Claim 5                                                                                                                          
                         Claim 5 is directed to a method of preparing a stabilized osmotic agent                                                  
                 comprising the following steps: providing a solution of starch dissolved in water and                                            
                 adding NaBH4  to the starch solution to reduce the starch.  We interpret the term                                                
                 “stabilized osmotic agents” in claim 5 to include maltodextrins reduced using water and                                          
                 NaBH4, in accordance with the specification.                                                                                     
                         According to the examiner, “the use of sodium borohydride [NaBH4] to reduce                                              
                 saccharides is well known in the art as Solomons teaches that aldoses and ketoses can                                            
                 be reduced with sodium borohydrides.”  Answer, page 4.  Solomons particularly                                                    
                 describes the reduction of D-glucose (a component of maltodextrin) to D-glucitol.                                                
                 Solomons, page 890.   Solomons does not teach the presence of water in the reaction                                              
                 According to the examiner, “Eliasson teaches that other non-cellulosic polysaccharides                                           
                 (e.g., arabinoxylans, xyloglucans and glucomannans) are preferentially extracted using                                           

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