Appeal No. 2002-1360 Page 2
Application No. 09/133,942
The examiner relies on the following references:
Craig et al. (Craig) 4,703,018 Oct. 27, 1987
Maehara et al. (Maehara), “Immunochemical Determination of the Serum Protein
Reacting with Antibody against Human Urinary Trypsin Inhibitor by Single Radial
Immunodiffusion: Use of Polyethylene Glycol,” Journal of Immunological
Methods, Vol. 80, pp. 117-123 (1985)
Claims 1-8 stand rejected under 35 U.S.C. § 102(b) as anticipated by
Maehara.
Claims 1-10 stand rejected under 35 U.S.C. § 103 as obvious in view of
Craig and Maehara.
We reverse.
Background
The specification discloses a “method for measuring the concentration or
activity of urinary trypsin inhibitor (UTI) contained in body fluids. The presence of
UTI was initially recognized in urine but its presence has been confirmed in body
fluids other than urine by subsequent studies.” Page 1. “[I]t has been reported
that the amount of UTI present in urine significantly increases in patients with
bacterial infections, malignant tumors . . ., renal diseases or myocardial
infarction, or patients having undergone surgical operations, pregnancy, or the
like.” Id.
Conventional methods of detecting UTI immunologically “include single
radial immunodiffusion (SRID), radioimmunoassay (RIA), enzyme immunoassay
(EIA), enzyme-linked immunosorbent assay (ELISA), latex agglutination
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