Ex Parte OHSHIRO - Page 8


                Appeal No. 2002-1360                                                  Page 8                  
                Application No. 09/133,942                                                                    

                      “A claim is anticipated only if each and every element as set forth in the              
                claim is found, either expressly or inherently described, in a single prior art               
                reference.”  Verdegaal Bros., Inc. v. Union Oil Co., 814 F.2d 628, 631, 2                     
                USPQ2d 1051, 1053 (Fed. Cir. 1987).  “[E]very limitation of a claim must                      
                identically appear in a single prior art reference for it to anticipate the claim.”           
                Gechter v. Davidson, 116 F.3d 1454, 1457, 43 USPQ2d 1030, 1032 (Fed. Cir.                     
                1997).                                                                                        
                      We agree that Maehara does not anticipate claim 1.  As Appellant points                 
                out, in the immunodiffusion assay used by Maehara, the anti-UTI antibodies are                
                incorporated into a solidified agar matrix.  See Mancini, page 235:  “By definition           
                the single-diffusion type of precipitin reaction is performed by incorporating one            
                of the two partners of the reaction, usually the antibody, into the agar gel, at a            
                uniform concentration, whereas the other reactant, usually the antigen, is                    
                introduced into a well from which it is allowed to diffuse into the gel.”  Maehara’s          
                disclosure confirms that the anti-UTI antibodies used were incorporated into the              
                agar gel.  See page 119, first full paragraph:  “The concentration of agar in the             
                gel plate was adjusted to 0.9% in 7 ml of veronal buffer . . . containing . . . various       
                amounts of anti-UTIγG.”  Anti-UTIγG is short for anti-UTI rabbit γ-globulin.  See             
                page 118.                                                                                     
                      Thus, in the assay disclosed by Maehara, the anti-UTI antibodies are                    
                attached to the insoluble agar gel support.  Maehara therefore does not                       
                anticipate claim 1.                                                                           







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