Ex Parte OHSHIRO - Page 11


                Appeal No. 2002-1360                                                 Page 11                  
                Application No. 09/133,942                                                                    

                teach a method in which antibodies “are not adhered to an insoluble support,” as              
                required by claim 1.  The rejection under 35 U.S.C. § 103 is reversed.                        
                                                Other Issues                                                  
                      As discussed above (pages 3-6), the art-accepted meaning of the term                    
                “agglutination” is an assay based on clumping of antibodies or antigens attached              
                to particulate antigens.  “Precipitation”, on the other hand, means formation of              
                visible complex between soluble antigen and soluble antibody.  Thus, the                      
                claimed assay would conventionally be described as based on precipitation,                    
                rather than agglutination.  If the examiner’s initial search of the claimed assay             
                was directed toward art disclosing an “agglutination” assay involving only soluble            
                components, it probably did not produce the most relevant prior art.                          
                      Upon return of this case, the examiner should review the search that was                
                performed and, if necessary, re-search the relevant sources for assays based on               
                precipitation rather than agglutination.  If a new search turns up prior art that             
                anticipates or renders obvious the instant claims, entry of new rejections under              
                35 U.S.C. § 102 and/or 35 U.S.C. § 103 would be appropriate.                                  
                      We also note that Appellant has submitted two Information Disclosure                    
                Statements since the Examiner’s Answer was filed.  The examiner should act on                 
                those IDSs as appropriate under 37 CFR § 1.97.                                                












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