Appeal No. 2003-0443 Page 3 Application No. 09/465,653 [i]t would have been obvious to one of ordinary skill in the art at the time of the invention to have modified the composition in Arora by replacing methyl salicylate with turpentine oil, as suggested by Deckner et al. and Went et al., because of the expectation of successfully producing a similar analgesic composition with equivalent effectiveness and skin penetration without adverse effects. As we understand the examiner’s rejection, since Deckner and Went disclose the equivalent function of turpentine, eucalyptus oil and methyl salicylate2, it would have been prima facie obvious to substitute turpentine for methyl salicylate in the composition disclosed by Arora. Notwithstanding the examiner’s arguments, the evidence relied upon by the examiner also leads a person of ordinary skill in the art to a composition comprising methyl salicylate, turpentine and alcohol, which is not the claimed invention. While the examiner suggests that turpentine, eucalyptus oil and methyl salicylate are equivalent in function, the examiner failed to provide any evidence as to why a person of ordinary skill in the art would have modified the Arora composition by substituting turpentine for methyl salicylate, and not for eucalyptus oil. Prima facie obviousness based on a combination of references requires that the prior art provide “a reason, suggestion, or motivation to lead an inventor to combine those references.” Pro-Mold and Tool Co. v. Great Lakes Plastics Inc., 75 F.3d 1568, 1573, 37 USPQ2d 1626, 1629 (Fed. Cir. 1996). [E]vidence of a suggestion, teaching, or motivation to combine may flow from the prior art references themselves, the knowledge of one of ordinary skill in the art, or, in some cases, from the nature of the problem to be solved. . . . The range of sources available, however, does not diminish the requirement for actual evidence. That is, the showing must be clear and particular. 2 Methyl salicylate is also known as wintergreen oil. See Arora, column 1, line 48.Page: Previous 1 2 3 4 5 6 NextLast modified: November 3, 2007