Ex Parte STILL et al - Page 9


                 Appeal No. 2003-1722                                                         Page 9                    
                 Application No. 09/041,343                                                                             

                 Taddei-Peters of several peptides comprising either proline or histidine residues.                     
                 The examiner reasoned that proline and histidine “have monocyclic Nitrogen                             
                 heterocy[c]les, which would read on the monocyclic nitrogen hetero cycle                               
                 template, substituted with two or more groups to which oligomers . . . are                             
                 attached.”  Examiner’s Answer, page 10.                                                                
                        Appellants argue that the instant claims contain limitations that are not met                   
                 by Taddei-Peters.  Appellants argue that the histidine-containing peptides do not                      
                 comprise a heterocyclic ring “substituted with two or more -O-, -NH- or –C=O” as                       
                 required by the claims.  With respect to the proline-containing peptides,                              
                 Appellants argue that the oligomers attached to the heterocycle do not form “an                        
                 amide, urea, urethane, sulfonamide or ester bond with said oligomer,” as                               
                 required.                                                                                              
                        Again, we agree with Appellants.  “Under 35 U.S.C. § 102, every limitation                      
                 of a claim must identically appear in a single prior art reference for it to anticipate                
                 the claim.”  Gechter v. Davidson, 116 F.3d 1454, 1457, 43 USPQ2d 1030, 1032                            
                 (Fed. Cir. 1997).  “Every element of the claimed invention must be literally                           
                 present, arranged as in the claim.”  Richardson v. Suzuki Motor Co., Ltd., 868                         
                 F.2d 1226, 1236, 9 USPQ2d 1913, 1920 (Fed. Cir. 1989).                                                 
                        Appellants have defined the claimed receptor compounds in a way that                            
                 excludes the prior art peptides from the scope of the claims.  The claims require                      
                 that the heterocyclic template be “substituted with” specified moieties; the most                      
                 reasonable interpretation of this limitation is that the specified moieties are                        
                 substituents of, and therefore directly attached to, the heterocyclic ring.                            





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