Ex Parte BUECHLER et al - Page 8



              Appeal No. 2003-2084                                                                Page 8                
              Application No. 08/241,061                                                                                

              examples directed to specific crosstalk inhibitors" (Examiner's Answer, page                              
              13)(emphasis in original).  Merely pointing to the breadth of a claim limitation does not                 
              establish that that claim limitation does not enjoy written descriptive support as required               
              by 35 U.S.C. § 112, first paragraph.  On this record, we do not find that the examiner                    
              has established a prima facie case of lack of written description for claims 98 and 99.                   
                     The rejection under 35 U.S.C. § 112, first paragraph (written description) of                      
              claims 98 and 99 is reversed.                                                                             
              3.  Enablement Rejection of Claims 98-102.                                                                
                     The examiner considers the specification to be enabling for compositions                           
              "comprising specific crosstalk Inhibitors (as in figures 1C-1F) and ligand conjugate,                     
              [sic]” but not for “any composition comprising ligand analogue conjugate and any                          
              crosstalk inhibitors."  Examiner's Answer, page 6.  In support of the rejection, the                      
              examiner provides an analysis of the factors set forth in In re Wands, 858 F.2d 731,                      
              737, 8 USPQ2d 1400, 1404 (Fed. Cir. 1988), i.e., (1) the quantity of experimentation                      
              necessary, (2) the amount of direction or guidance presented, (3) the presence or                         
              absence of working examples, (4) the nature of the invention, (5) the state of the prior                  
              art, (6) the relative skill of those in the art, (7) the predictability or unpredictability of the        
              art, and (8) the breadth of the claims.                                                                   
                     We first point out that application 07/683,456 is stated to be a parent application                
              of this application.  U.S. Patent No. 5,525,524 ('524 patent) also traces its parentage to                
              application 07/683,456.  In response to an obviousness-type double patenting rejection                    
              based upon the claims of the '524 patent, appellants have filed a terminal disclaimer.                    
              Paper No. 43, April 23, 1999.  Claim 3 of the '524 patent reads as follows:                               




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