Beckmann et al v. Lyman - Page 3




                Interference No. 105,099                                                                         Paper 25                     
                Hannum v. Immunex Corp.                                                                             Page 3                    
                         Immunex 449 claims 1-15                                                                                              
        [7]     The Immunex 806 claims and the Hannum 882 claims are drawn to flt-ligand                                                      
                polypeptides [2003; 2005].                                                                                                    
        [8]     The Immunex 449 claims and the Hannum 168 claims are drawn to antibodies (or kits                                             
                using such antibodies) for the flt3 ligand as each party has claimed the ligand [2004;                                        
                2006].                                                                                                                        
        [9]     The Immunex claims all define the claimed invention in terms of relatively long                                               
                subsequences of Immunex SEQ ID NO:2.5                                                                                         
        [10] The Hannum claims are generic to the Immunex claims in the sense that they recite                                                
                properties of the defining flt3-ligand polypeptide, including relatively short                                                
                subsequences, rather than reciting a continuous, relatively large subsequence as                                              
                Immunex does (e.g., Paper 22, unopp'd facts 10 and 18).                                                                       
        [11] The Immunex species claims defined by its SEQ ID NO:2 anticipate Hannum's generic                                                
                claims.6                                                                                                                      
        [12]    According to Hannum, nothing in its claims or specification teach or suggest the specific                                     
                polypeptide sequence of Immunex SEQ ID NO:2, which is central to the definition of the                                        
                Immunex invention in the involved Immunex claims (e.g., Paper 22, unopp'd facts  17                                           
                and 20).                                                                                                                      


                         5  Immunex 806 claims 52 and 56 and 449 claims 1, 6, and 11 are defined in terms of a deposited                      
                vector, but neither party has argued that this vector represents a sequence different from the relevant portions              
                of Immunex SEQ ID NO:2.                                                                                                       
                         6  The Hannum kit claims would not be anticipated, but their separate patentability has not been                     
                separately argue d.  Presumab ly Hannum c oncedes for the  purpose of this m otion that the use of antibo dies to             
                a known polypep tide in the form of a  kit is too obvious to co ntest.                                                        





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