Ex Parte QUAN et al - Page 7


                 Appeal No.  2003-1679                                                        Page 7                  
                 Application No.  08/993,010                                                                          
                 invention.  Akzo N.V., Aramide Maatschappij v.o.f. v. United States Int’l Trade                      
                 Comm’n, 808 F.2d 1471, 1481, 1 USPQ2d 1241, 1246 (Fed. Cir. 1986).                                   
                        We note the examiner’s assertion (Answer, page 15), “[i]t is the position of                  
                 the examiner that Figura in view of Xiang clearly provides a reasonable                              
                 expectation of success in detecting the presence of humoral Type I and Type II                       
                 antibodies (see Figure 5) indicative of H.[ ]pyloir Type I or Type II strains infecting              
                 the patient.”  However, as discussed above, on this record, neither Figura nor                       
                 Xiang provide a correlation of the presence or absence of specific antibodies to                     
                 infection with Type I or Type II H. pylori.  While the examiner has asserted that a                  
                 correlation exists, the evidence of record does not support this assertion.  We                      
                 remind the examiner that “to imbue one of ordinary skill in the art with knowledge                   
                 of the invention in suit, when no prior art reference or references of record                        
                 convey or suggest that knowledge, is to fall victim to the insidious effect of a                     
                 hindsight syndrome wherein that which only the inventor taught is used against                       
                 its teacher.”  W.L. Gore & Associates, Inc. v. Garlock, Inc., 721 F.2d 1540, 1553,                   
                 220 USPQ 303, 312-13 (Fed. Cir. 1983).                                                               
                        Crabtree, relied upon by the examiner (Answer, page 7) to teach “the use                      
                 of a detectably labeled anti-human immunoglobulin antibodies…,” fails to make                        
                 up for the deficiencies in the combination of Figura and Xiang.  Accordingly, we                     
                 reverse the rejection of claims 1-3, 6-10 and 13-17 under 35 U.S.C. § 103 as                         
                 being unpatentable over Figura in view of Xiang and Crabtree.                                        
                 Figura in view of Xiang and Crabtree and further in view of Telford:                                 








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