Ex Parte MCDONNELL et al - Page 8


              Appeal No. 2003-2091                                                               Page 8                
              Application No. 09/266,465                                                                               

              Bcl-2 family member genes . . . would anticipate claims reciting these limitations.”  Id.,               
              pages 6-7.                                                                                               
                     The facts of this case are not analogous to those of Petering.  At issue in                       
              Petering was a claimed chemical compound that had been rejected over a prior art                         
              patent (Karrer).  See id. at 995-96, 133 USPQ at 276-77.  Karrer disclosed a similar                     
              compound having substituents at various positions that could be, but were not                            
              necessarily, the same as those in the claimed compound.  The court concluded that the                    
              generic disclosure did not anticipate Petering’s claims:  “Even though appellants’                       
              claimed compounds are encompassed by [Karrer’s] broad generic disclosure, we do not                      
              think this disclosure by itself describes appellants’ invention, as defined by them in any               
              of the appealed claims, within the meaning of 35 U.S.C. 102(b).”  Id. at 1000, 133                       
              USPQ at 279 (emphasis in original).                                                                      
                     The court noted, however, that Karrer also described preferred substituents for                   
              each of the variable positions.  When the disclosed preferences were taken into                          
              account, the court found that only 20 compounds were within the preferred subgenus                       
              taught by Karrer.  See id. at 1000, 133 USPQ at 279-80.  The court concluded that “one                   
              skilled in this art would, on reading the Karrer patent, at once envisage each member of                 
              this limited class.”  Id. at 1001, 133 USPQ at 280 (emphasis in original).                               
                     In the present case, by contrast, Zhang lists at least 57 promoters that could be                 
              used in the disclosed adenoviral vectors.  See Tables 2 and 3 in columns 29-30.  In                      
              addition, Appellants have asserted (and the examiner has not disputed) that Zhang                        
              discloses nearly 100 different therapeutic agents that could be used.  Thus, it would                    
              appear that Zhang discloses a genus of adenoviral vectors comprising nearly 5700                         





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