Ex Parte Matzinger et al - Page 14


                 Appeal No.  2003-2146                                                        Page 14                  
                 Application No.  09/546,143                                                                           
                        For the foregoing reasons, we reverse the rejection of claim 17 under 35                       
                 U.S.C. § 102(b) as anticipated by Krogsgaard-Larsen.                                                  
                 Adams:                                                                                                
                        According to the examiner (Answer, page 9), “Formula X in [appellants’]                        
                 claim 23 inherently embraces compound 20 on page 2356 [of Adams].  Formula                            
                 XI in [appellants’] claim 25 inherently embraces compound 21 on page 2357 [of                         
                 Adams].”  However, as appellants point out (Brief, pages 7-8), the compound                           
                 taught by Adams is in the trans-configuration, not the cis-configuration as                           
                 required by appellants’ claimed invention.  To emphasize this “fundamental                            
                 principle” of stereo-chemistry, we note that Adams resolve the enantiomers of                         
                 compound 21.  Scheme 3 on page 2357 of Adams, illustrates the two                                     
                 enantiomeric forms (compound 21a and 21b) of the trans configuration of                               
                 compound 21.  See Adams, bridging sentence, page 2356, column 2 – page                                
                 2357, column 1; and Scheme 3, page 2357.                                                              
                        For the foregoing reasons, we reverse the rejection of claims 23 and 25                        
                 under 35 U.S.C. § 102(b) as anticipated by Adams.                                                     
                 Barbier:                                                                                              
                        According to the examiner (Answer, page 9), “Formula XI in [appellants’]                       
                 claim 25 inherently embraces compounds B1-B23 listed on columns 18-21 [of                             
                 Barbier].  However, as appellants point out (Brief, page 8), “[t]he exemplified                       
                 compounds of Barbier et al. are all in the trans [con]formation.”4  Therefore,                        
                 appellants assert (id.), “the teaching of the trans [con]formation does not                           
                 anticipate the instantly claimed, structurally distinct, cis [con]formation.”                         







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