Ex Parte Hof et al - Page 2



         Appeal No. 2004-0971                                                       
         Application No. 09/887,933                                                 

              wherein said strong base is chemically reactive with                  
         water.                                                                     

         The examiner relies upon the following reference as                        
         evidence of unpatentability:                                               
         Hijiya et al. (Hijiya)       5,679,857       Oct. 21, 1997                 

              Claims 12 through 22 stand rejected under 35 U.S.C.                   
         § 103 as being obvious over Hijiya.                                        

                                   OPINION                                          
              In the paragraph bridging pages 3 and 4 of the Brief,                 
         appellants argue that there is no teaching or suggestion in                
         Hijiya of the racemization of a Schiff base of a primary                   
         amide of an amino acid.1  Appellants argue that Hijiya                     
         discloses racemization of a Schiff base of a secondary                     
         amino acid amide.  On page 4 of the Brief, appellants argue                
         that Hijiya does not provide a suggestion or motivation to                 
         modify the secondary amino acid amides to arrive at the                    
         primary amino acid amides used in the claimed invention.                   
         On page 5 of the Brief, appellants also argue that there is                
         no indication of why a skilled artisan would expect that a                 
         primary amide of an amino acid would function equivalently                 
         in the teachings of Hijiya.  See also pages 2-3 of the                     
         Reply Brief.                                                               
                                                                                   
         1 The examiner agrees that Hijiya does not teach a primary amide           
         of an amino acid.  Answer, page 3.                                         
                                       2                                            




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