Ex Parte Trant - Page 9


                 Appeal No. 2004-0974                                                          Page 9                    
                 Application No. 10/117,169                                                                              

                 composition for improving male fertility.  However, we do not agree with the                            
                 examiner that the references would have suggested adding to such a                                      
                 composition the additional components required by claim 5 – vitamin E, zinc, and                        
                 at least two B vitamins.                                                                                
                        The examiner relies on Balch and Ashmead as suggesting these                                     
                 components.  The examiner notes that “Balch teaches using vitamin E, zinc, and                          
                 vitamin B6 to treat impotence.”  Impotence, however, is not the same as male                            
                 infertility.  The problem addressed by Zheng, Scott, and Dawson is sperm                                
                 viability and/or motility, while the problem addressed by Balch is inability to                         
                 engage in sexual intercourse.  See page 338.  The examiner has not adequately                           
                 explained why those skilled in the art would have expected that the nutritional                         
                 supplements discussed by Balch would have any effect on sperm viability or                              
                 motility; nor has the examiner explained why, in the absence of such an                                 
                 expectation, those skilled in the art would have been motivated to add those                            
                 supplements to the composition suggested by Zheng, Scott, and Dawson.                                   
                        The examiner characterizes Ashmead as “teach[ing] using vitamin B12 to                           
                 improve male sexual health.”  We do not agree with this characterization of                             
                 Ashmead’s disclosure.  Ashmead teaches that a composition comprising                                    
                 manganese, iron, and zinc, in the form of amino acid chelates, stimulates                               
                 gonadotropin hormone production.  Abstract.  “In the male both libido and                               
                 spermatogenesis are improved by the oral administration of the composition.”  Id.                       
                 While Ashmead discloses that such compositions can also contain vitamins, it                            
                 does not suggest that the vitamins themselves have any beneficial effect on                             





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