Ex Parte Haslwanter et al - Page 2


                Appeal No.  2004-1188                                                   Page 2                 
                Application No.  09/940,784                                                                    
                           weight about 360,000; and a water-soluble polyethylene glycol; the                  
                           total concentration of the linear polymer ingredients being about 0.5               
                           to about 15 percent by weight/volume.                                               
                      The references relied upon by the examiner are:                                          
                Shimizu et al. (Shimizu)        4,728,509                 Mar.  1, 1988                       
                Parnell                         5,015,474                 May 14, 1991                        
                Gilbert et al. (Gilbert)        5,116,847                  May 26, 1992                        
                Rybacki et al. (Rybacki), “Auxiliary Substances in Technology of Drug Form,”                   
                Library of a Pharmicist, Vol. 7, pp. 1-12 (1980)                                               
                                         GROUNDS OF REJECTION                                                  
                      Claims 15-17 and 21-28 stand rejected under 35 U.S.C. § 103 as being                     
                unpatentable over the combination of Shimizu, Gilbert and Parnell.                             
                      Claims 18-20 and 29-33 stand rejected under 35 U.S.C. § 103 as being                     
                unpatentable over the combination of Shimizu, Gilbert and Parnell, further in                  
                view of Rybacki.                                                                               
                      We reverse.                                                                              
                                                DISCUSSION                                                     
                The combination of Shimizu, Gilbert and Parnell:                                               
                      According to the examiner (Answer, page 3), Shimizu disclose an                          
                aqueous nasal spray composition comprising, inter alia, a drug and                             
                polyvinylpyrrolidone (PVP) having an average molecular weight of about 25,000-                 
                120,000 daltons.  The examiner recognizes, however, that Shimizu does not                      
                teach the (1) use of two or more PVPs having different average molecular                       
                weights, or (2) oxymetazoline hydrochloride.  Answer, page 4.  The examiner                    
                relies on Gilbert and Parnell to make up these deficiencies.                                   








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