Barton et al or Fischhoff et al v. Adang et al. - Page 38




          Interference 103,781                                                        

          May 3, 1995, or Claims 13-14 of Adang’s U.S. Patent 5,380,831,              
          would have been obvious in view of any other claim designated as            
          corresponding to Count 2, with or without the combined teachings            
          of all the prior art of record, is a question of law.                       
               Fischhoff argues that there is no “motivation or suggestion            
          to make the particular species from the teaching of the genus”              
          (Paper No. 224, para. bridging pp. 10-11).  We do not agree                 
          that there is no motivation or suggestion to make and use the               
          particular species claimed by Fischhoff and by Adang.  The                  
          motivation or suggestion to make and use a chemical species                 
          defined in terms of chemical structure, formula, name or                    
          properties need not be explicit.  The motivation or suggestion to           
          make and use a particular chemical species may be implicit from a           
          prior art genus of definitive scope.  For example, In re Payne,             
          606 F.2d 303, 203 USPQ 245 (CCPA 1979), teaches at 314, 203 USPQ            
          at 255:                                                                     
               When prior art compounds essentially “bracketing” the                  
               claimed compounds in structural similarity are all known               
               as pesticides, one of ordinary skill in the art would                  
               clearly be motivated to make those claimed compounds in                
               searching for new pesticides.                                          
          Here, one might reasonably conclude that a person having ordinary           
          skill in the art would have been “motivated” to make and use the            
          particular species claimed by Fischhoff or Adang by the desire to           
          (1) reduce the number of polyadenylation and ATTTA sequences in             

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