Ex Parte SEED et al - Page 4


                 Appeal No. 2004-1736                                                          Page 4                    
                 Application No. 09/243,008                                                                              

                 possession of the claimed invention.  As the claims stand or fall together, see                         
                 Appeal Brief, page 5, we focus our analysis on claim 44.                                                
                        According to the rejection, “[a]pplicant has no support in the originally filed                  
                 claims or specification for the genus phrase language ‘an intracellular domain                          
                 that does not signal to said cell to destroy a receptor-bound target cell or                            
                 receptor-bound target infective agent,’ present in amended base claims 44 and                           
                 79.”  Examiner’s Answer, page 3.                                                                        
                        As noted by our reviewing court, the Court of Appeals for the Federal                            
                 Circuit,                                                                                                
                                In order to satisfy the written description requirement, the                             
                        disclosure as originally filed does not have to provide in haec verba                            
                        support for the claimed subject matter at issue.  Nonetheless, the                               
                        disclosure must convey with reasonable clarity to those skilled in                               
                        the art that the inventor was in possession of the invention.  Put                               
                        another way, one skilled in the art, reading the original disclosure,                            
                        must immediately discern the limitation at issue in the claims.  That                            
                        inquiry is a factual one and must be assessed on a case-by-case                                  
                        basis.                                                                                           
                 Purdue Pharma v. Faulding Inc., 230 F.2d 1320, 1323, 56 USPQ2d 1481, 1483                               
                 (Fed. Cir. 2000) (citations omitted) (emphasis added).  We agree with appellants                        
                 that the disclosure as originally filed reasonably conveys to one skilled in the art                    
                 that the inventor(s), at the time the application was filed, had possession of the                      
                 claimed invention.                                                                                      
                        Appellants cite page 48 of the specification, lines 31-33, which describes a                     
                 chimera that possesses a transmembrane domain joined to an intracellular                                
                 domain of only three amino acids, wherein the chimera is capable of signaling                           
                 through its transmembrane domain.  See Appeal Brief, page 10.  Appellants also                          





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