Ex Parte Metzner et al - Page 8


                Appeal No. 2005-0192                                                                                 Page 8                    
                Application No. 09/809,021                                                                                                     

                apparently need not even contain human thrombin in order to be “suitable for                                                   
                therapeutic purposes.”                                                                                                         
                         We conclude that the compositions disclosed by Lorne and Allary reasonably                                            
                appear to meet all of the limitations of instant claim 18.  The burden therefore shifts to                                     
                Appellants to provide evidence to the contrary.  See In re Best, 562 F.2d 1252, 1255,                                          
                195 USPQ 430, 433 (CCPA 1977) (“[W]here the Patent Office has reason to believe                                                
                that a functional limitation asserted to be critical for establishing novelty in the claimed                                   
                subject matter may, in fact, be an inherent characteristic of the prior art, it possesses                                      
                the authority to require the applicant to prove that the subject matter shown to be in the                                     
                prior art does not possess the characteristic relied on.”).                                                                    
                         Appellants have provided no evidence to show that the thrombin- and                                                   
                benzamidine-containing eluate disclosed by the prior art is not “suitable for therapeutic                                      
                purposes.”  Since the prior art composition reasonably appears to meet all the                                                 
                limitations of instant claim 18, and Appellants have provided no evidence that it does                                         
                not, we affirm the rejection of claim 18 as anticipated by either Allary or Lorne.  Claims                                     
                35 and 37 fall with claim 18.                                                                                                  
                2.  Obviousness                                                                                                                
                         The examiner rejected claims 18, 19, and 35-38 as obvious over either Allary or                                       
                Lorne, combined with Hanada, Brezniak, and Altshuler.  As noted above, all of the                                              
                claims stand or fall together.  Therefore, we need only consider claim 18; claims 19 and                                       
                35-38 stand or fall with claim 18.                                                                                             
                         We have already concluded the claim 18 is anticipated by either of Allary or                                          
                Lorne.  Therefore, claim 18 is also obvious in view of either Allary or Lorne, standing                                        





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