Ex Parte VALLE et al - Page 7


                  Appeal No.  2005-0394                                                            Page 7                   
                  Application No.  08/940,692                                                                               
                         As set forth in In re Kotzab, 217 F.3d 1365, 1369-70, 55 USPQ2d 1313,                              
                  1316 (Fed. Cir. 2000):                                                                                    
                         A critical step in analyzing the patentability of claims pursuant to                               
                         section 103(a) is casting the mind back to the time of invention, to                               
                         consider the thinking of one of ordinary skill in the art, guided only                             
                         by the prior art references and the then-accepted wisdom in the                                    
                         field. … Close adherence to this methodology is especially                                         
                         important in cases where the very ease with which the invention                                    
                         can be understood may prompt one “to fall victim to the insidious                                  
                         effect of a hindsight syndrome wherein that which only the invention                               
                         taught is used against its teacher.”                                                               
                                                            …                                                               
                         Most if not all inventions arise from a combination of old elements.                               
                         … Thus, every element of a claimed invention may often be found                                    
                         in the prior art. … However, identification in the prior art of each                               
                         individual part claimed is insufficient to defeat patentability of the                             
                         whole claimed invention. … Rather, to establish obviousness based                                  
                         on a combination of the elements disclosed in the prior art, there                                 
                         must be some motivation, suggestion or teaching of the desirability                                
                         of making the specific combination that was made by the applicant.                                 
                         [citations omitted]                                                                                
                  In other words, “there still must be evidence that ‘a skilled artisan, … with no                          
                  knowledge of the claimed invention, would select the elements from the cited                              
                  prior art references for combination in the manner claimed.’”  Ecolochem Inc. v.                          
                  Southern California Edison, 227 F.3d 1361, 1375, 56 USPQ2d 1065, 1075-76                                  
                  (Fed. Cir. 2000).  On this record, the examiner has provided, and we find no                              
                  evidence of a suggestion in the prior art to screen for cells having the specific                         
                  growth rate set forth in appellants’ claims.  Accordingly, we reverse the rejection                       
                  of claims 23-27, 29-31, 33-38, 42, 44, 46, 49 and 50 stand rejected under 35                              
                  U.S.C. § 103 as being unpatentable over Frost, Holms, Ingrahm and Saier.                                  










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