Ex Parte Daluge et al - Page 5




              Appeal No. 2005-0838                                                                                        
              Application No. 10/174,414                                                                                  


                     We have carefully considered the respective positions of both the appellants and                     
              the examiner and find ourselves in substantial agreement with that of the examiner.                         
              Accordingly, we affirm both Rejection I and II.                                                             


                                              Background and Discussion                                                   
                     The present invention is directed to a method of using substituted phenylated                        
              purines as prophylactics for any inflammatory condition or immune disorder associated                       
              with the infiltration of leukocytes into inflamed tissue.  Specification, p. 4, lines 24-31.                
              Since both rejections turn on the same issue; i.e., whether the teachings of the                            
              specification would have enabled one skilled in the art “to make and use” the claimed                       
              method of prophylaxis, we have considered them together.                                                    
                     In brief, the examiner argues that given the breadth of the claims, the                              
              unpredictable nature of the invention, the lack of any working examples, the level of skill                 
              in the art, and the state of the art, the teachings of the specification would not have                     
              enabled one skilled in the art to make and use the invention without undue                                  
              experimentation.  In re Wands,  858 F.2d 731, 737, 8 USPQ2d 1400, 1404 (Fed. Cir.                           
              1988).  The examiner relies on twelve (12) references which disclose that there are no                      
              known methods of preventing several of the claimed diseases and disorders using                             
              pharmaceutical compounds, for support.  Attention is directed to pages 4-8 of the                           
              examiner’s Answer for a succinct summary of the teachings of the applied prior art.                         

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